KISSWIN.DE-Blog

07.10.2012
22:42

Biologen verlieren den Blick f?¼r die Natur

Das Klavier verstummt und die Querflöte trällert noch ein, zwei Akkorde bevor die letzten Klänge der Bach-Sonate im Applaus untergehen. Die beiden Musiker sind sicher schon über 80 Jahre alt. Es handelt sich um Jerrold Meinwald, einen emeritierten Professor aus Cornell, und seine Frau Charlotte. Ihre Darbietung ist einer der Höhepunkte am ersten Abend des Ethomics-Meetings in Jena. Organisiert wurde die kleine Konferenz vom MPI für Chemische Ökologie.

Der Begriff Ethomics war mir auch neu und ich musste erst mal googeln. Nun, da Biologen den genetischen Code der ganzen Biosphäre entschlüsseln, ist es an der Zeit die Bedeutung des genetischen Materials für das Überleben des einzelnen Organismus zu untersuchen. Und zwar nicht nur in einem Reaktionsgefäß im Labor, sondern im Kontext der natürlichen Umgebung eines Lebewesens. Und darum geht es bei Ethomics.

Jerrold Meinwald hat jahrzehntelang mit Thomas Eisner, einem Biologen aus Cornell, gearbeitet. Thomas Eisner ist letztes Jahr verstorben und dieser Abend stellte eine kleine Hommage an sein Lebenswerk dar. Neben ehemaligen Kollegen und Freunden kommen auch einstige Doktoranden zu Wort. In einer Broschüre finden sich viele Nachrufe von bedeutenden Mitstreitern (z.B. in der New York Times: http://www.nytimes.com/2011/04/05/science/05angier.html?pagewanted=all). Thomas Eisner hat in seiner langjährigen Forschertätigkeit oft das gemacht, was den modernen Biologen von heute abhandengekommen ist: die Natur beobachtet. Vor allem Insekten hatten es ihm angetan. Glücklicherweise standen ihm in Cornell exzellente Chemiker, wie z.B. Jerrold Meinwald, an seiner Seite, die er für seine biologische Forschung begeistern konnte. Mit ihrer Hilfe entschlüsselte er viele chemische Signale die Insekten untereinander, z.B. bei der Paarung, austauschen. Laut Jerrold Meinwald war die Untersuchung der Käferexkrete aus Sicht eines Chemikers nicht gerade ein Hochgenuss, da deren chemische Zusammensetzung zuweilen recht simpel ist / war. Eisner schaffte es jedoch, die Analyse der Verbindungen mit ihrer Funktion in der Natur zu verknüpfen und war somit ein Vorreiter der Chemischen Ökologie. 

Die Vorträge an diesem Abend machten noch ein Problem moderner biologischer Forschung deutlich: Biologische Fachzeitschriften strotzen heutzutage von Forschungsergebnissen, die gerade mal durch Untersuchungen an einer Handvoll Modelllebewesen gewonnen werden. Dazu gehören z.B. Mensch, Maus, Ackerschmalwand (ein gerade mal einige Dezimeter großes Unkraut), Fruchtfliege, Zebrafisch und ein unscheinbarer Fadenwurm. Diese Organismen werden Molekül für Molekül und Gen für Gen akribisch untersucht. Allerdings hat ein Großteil der Forscher ihr Forschungsobjekt (Humangenetiker ausgenommen) noch nie in freier Natur gesehen. Das ist insofern auch nicht nötig, um die Interaktionen von Proteinen miteinander zu untersuchen, oder welche Gene für bestimmte Entwicklungsprozesse verantwortlich sind. Natürlich ist diese Grundlagenforschung ist sehr wichtig, allerdings verliert sich bei vielen Wissenschaftlern der Blick im Detail und zudem ist es fraglich, ob die gewonnen Erkenntnisse 1:1 auf andere Organismen übertragen werden können. Ich möchte mich da nicht ausgrenzen, bin aber froh, dass meine Ausbildung auch im Freiland stattfand (siehe http://www.kisswin.de/karrierewege/blog.html?tx_t3blog_pi1[blogList][showUid]=6&tx_t3blog_pi1[blogList][year]=2011&tx_t3blog_pi1[blogList][month]=06&tx_t3blog_pi1[blogList][day]=01&cHash=32bfb7f864b1e3384a23f4b7580809d5).

Das Eisnerische Prinzip wieder aufzugreifen,  war ein Schwerpunkt dieses Ethomics meetings. Wenn wir verstehen wollen, wie einzelne Gene das Überleben von Arten sichern, dann müssen wir die Tore der Labore öffnen und wieder vermehrt einen Blick in die Natur wagen.

Das Ende dieses Abends markiert eine Diashow mit vielen genialen Bildern die Tom Eisner von der Natur gemacht hat, begleitet von Charlotte und Jerrold Meinwalds`zauberhaften Bach-Interpretationen.

 

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Dr. Dorothea Meldau
Biologin
Dr. Stefan Meldau
Biologe
Abschluss der Promotion 2013

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